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Bethesda North Marriott Hotel and Conference Center

2019 年 04 月 08 日 1:00 下午 - 2019 年 04 月 10 日 4:00 下午

5701 Marinelli Road, , North Bethesda, MD 20852 , USA

DIA/FDA Biostatistics Industry and Regulator Forum

Session 11: Causality, Artificial Intelligence, and Big Data

Session Chair(s)

Rima  Izem, PhD

Rima Izem, PhD

Associate Director Statistical Methodology

Novartis, Switzerland

Representative Invited

Representative Invited

FDA, United States

William  Wang, PhD

William Wang, PhD

Executive Director

Merck & Co, Inc, United States

Life is full of intended or unintended cause and effect. Understanding and utilizing these causal relationships have been at the core of human learning and human intelligence. With great technology advance in this digital age, big data is fueling our imagination and innovation for Machine Learning and Artificial Intelligence. In this session, we will invite a few top experts to examine what all these mean for our pursuit of causality. We will ask the questions of why, what, how we should handle causal inference with/without randomization in the context of biopharmaceutical research. Various approaches in design and analysis for causal inference will be discussed. We will also look to the future and discuss the role biopharmaceutical statisticians should play in the machine powered data driven casual inference for pharmaceutical innovation.

Speaker(s)

Elias  Bareinboim

Causal Inference and Data-Fusion

Elias Bareinboim

Purdue University, United States

Professor

Mark Johannes van der Laan, PhD

Targeted Machine Learning for Generating Real-World Evidence from Observational Data

Mark Johannes van der Laan, PhD

UC Berkeley, United States

Professor in Biostatistics and Statistics

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