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Grand Hyatt Washington at Washington Center

2015 年 09 月 09 日 7:00 上午 - 2015 年 09 月 11 日 12:00 下午

1000 H Street, NW, , Washington, DC 20001-4310 , USA

DIA/FDA Oligonucleotide-Based Therapeutic Conference 2015

Interact with renowned investigators and key health authorities to learn about the latest developments in oligonucleotide-based therapeutics. New for 2015—Enhanced poster session.

Session 2A: CMC Track: Emerging Trends

Session Chair(s)

Stephen R Sofen, PHD

Stephen R Sofen, PHD

CMC Team Director

Biogen Idec, United States

This session will focus on the emerging field of mRNA therapeutics and feature two presentations followed by a panel discussion. The presenters will discuss CMC challenges associated with the manufacture of long coding RNAs. Potential topics for discussion include:
• Purity requirements for long RNA
• RNA stability

Speaker(s)

Gary  Lee, PHD

cGMP Manufacturing of mRNA Products: Considerations and Challenges

Gary Lee, PHD

Sangamo BioSciences, Inc., United States

Research Scientist

Andreas  Kuhn, PHD

Manufacturing of Long, Coding RNAs

Andreas Kuhn, PHD

Biontech SE, Germany

Senior Vice President RNA Biochemistry & CMC Development

René  Thürmer, PHD

Q&A Panel Discussion (Joining the Speakers):

René Thürmer, PHD

Federal Institute for Drugs and Medical Devices, Germany

Quality Assessor

James D. Thompson, PHD

James D. Thompson, PHD

Moderna Therapeutics , United States

CMC Therapeutic Area Lead

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