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NH Buenos Aires City

Sep 29, 2025 11:00 AM - Oct 01, 2025 12:00 PM

Bolívar 160, C1066AAD Buenos Aires, Argentina

Latin America Annual Meeting

Take advantage of opportunities for networking and knowledge sharing with key stakeholders influencing the advancement and implementation of initiatives in Latin America and the Caribbean.

Session 6, Track A: Clinical Trials Operations and Management – Designing Quality into Innovative Clinical Trials

Session Chair(s)

Monica  Lizano, MD, MBA

Monica Lizano, MD, MBA

Global Director, Clinical Quality Management

Merck Chile, Chile

Clinical trials are evolving to better meet participant expectations by enhancing data collection methods, incorporating decentralized and pragmatic elements. The ICH E6(R3) Good Clinical Practice guidelines have adapted to reflect these advancements, highlighting the importance of quality by design (QbD), integrating quality management guidance, and actively promoting engaging key stakeholders to implement quality by design in protocol development.

Early identification of Critical to Quality (CtQ) factors during protocol design, along with understanding the associated risks and their mitigations, plays a vital role in shaping the protocol and the operational and quality plans that direct trial conduct. This proportionate, risk-based approach ultimately leads to clinical trials that are fit for purpose—ensuring that all important trial components effectively address the research question, support the generation of reliable results, and prioritize participant safety. This presentation will delve into how publicly available tools can aid companies in navigating the implementation of ICH E6(R3), providing examples that illustrate these concepts.

Learning Objective : At the conclusion of this session, participants should be able to:
  • Recognize changes in regulations to address the evolution in clinical trial design
  • Identify innovative clinical trial design and the challenges in their implementation
  • Define the quality by design concept and the quality risk management process

Speaker(s)

Monica  Lizano, MD, MBA

Designing Quality into Clinical Trials

Monica Lizano, MD, MBA

Merck Chile, Chile

Global Director, Clinical Quality Management

Cristina Elena  Papayannis, DrMed

Clinical Trial Operations and Management: Quality Design for Innovative Clinical Trials

Cristina Elena Papayannis, DrMed

ANMAT Ministry of Health, Argentina

Medical Doctor

Florencia  Braga Menendez

Patient Perspective

Florencia Braga Menendez

ALAPA Alianza Argentina de Pacientes, Argentina

Directora de Proyectos

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