*Short Courses require an additional registration fee. You do not need to be registered for the forum to attend*

Group sequential and adaptive designs in clinical trials are well-known to increase efficiency in drug development. In the appropriate scenarios, they offer the flexibility of mid-trial modifications that reduce sample size or overall timeline. This short course will start with introducing the fundamental theory of group sequential and adaptive designs. The second part of the course will dive deeper into related topics, such as inference following such designs, their practical implementation, and real-life examples. Thereafter, more complex designs combining group sequential elements with multiple testing procedures will be covered. Finally, the session will close with recommendations including regulatory guidance. This course is for statistical researchers in the pharmaceutical industry, academic institutions, regulatory agencies, and statistics students with basic or intermediate level of knowledge about clinical trial design. It is oriented towards practitioners who (i) are interested in using group sequential / adaptive designs in medical product development; (ii) are interested to understand the methodological perspectives; and (iii) are interested to learn the practical aspects related to their implementation.