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DIA 2021 Global Annual Meeting


SAS Institute Inc., JMP Division Innovation Theater: Obtain Robust Estimates from Critical Quality Attribute Models Through Limits of Detection (LOD) Censoring

Session Chair(s)

  SAS Institute Inc. JMP Division

SAS Institute Inc. JMP Division

  • JMP, A Business Unit of SAS, United States
Complex laboratory methods are commonly used to evaluate critical quality attributes of drugs in development and throughout the product lifecycle. Instruments have validated ranges for obtaining data and results are commonly obtained that are beyond the limits of detection. New techniques appropriately deal with limits of detection and control for extrapolation within statistical models. Use of such techniques yield significant improvements in the precision and accuracy of model estimates.

Speaker(s)

Rob  Lievense

Rob Lievense

  • JMP Senior Systems Engineer, SAS
  • SAS Institute Inc., JMP Division, United States
Byron  Wingerd

Byron Wingerd

  • JMP Senior Systems Engineer, SAS
  • SAS Institute Inc., JMP Division, United States