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Bethesda North Marriott Hotel and Conference Center

Oct 28, 2019 7:00 AM - Oct 30, 2019 12:30 PM

5701 Marinelli Road, , North Bethesda, MD 20852 , USA

DIA/FDA Oligonucleotide-Based Therapeutics Conference

Session 1: Rare Diseases

Session Chair(s)

Philip  Gatti, PhD

Philip Gatti, PhD

Pharmacologist, FDA, United States

Edward M. Kaye, MD

Edward M. Kaye, MD

Chief Executive Officer, Stoke Therapeutics, United States

Personalized medicine is a major goal in development of new drugs and in medical care in general. Unfortunately, this is very difficult considering the myriad of genetic variations and pathological mutations in people. Oligonucleotide treatments, however, allow for the targeted development of treatment in not only rare and ultrarare diseases, but recently for one person. In today’s Rare Diseases session, the speakers will demonstrate examples of this type of development program with its successes and challenges.

Speaker(s)

Timothy W. Yu, MD, PhD

Timothy W. Yu, MD, PhD

Associate Professor, Harvard Medical School; Division of Genetics and Genomics, Boston Children’s Hospital, United States

Batten Disease Patient Story Update

Matt R. Buck, JD

Matt R. Buck, JD

Vice President, Regulatory Affairs, Ionis Pharmaceuticals, Inc., United States

Ultra-Rare Disease Development Scenario

Lucas  Kempf, MD

Lucas Kempf, MD

Vice President, RCS, Parexel, United States

Ultra-Rare Disease Development Scenario

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