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Bethesda North Marriott Hotel and Conference Center

Apr 08, 2019 1:00 PM - Apr 10, 2019 4:00 PM

5701 Marinelli Road, , North Bethesda, MD 20852 , USA

DIA/FDA Biostatistics Industry and Regulator Forum

Session 1:Promoting Complex Innovative Trial Designs: An Update and Discussion on the Pilot Meeting Program

Session Chair(s)

Dionne  Price, PhD

Dionne Price, PhD

Deputy Director, Office of Biostatistics, OTS, CDER, FDA, United States

Cristiana  Mayer, DRSc, PhD

Cristiana Mayer, DRSc, PhD

Head of Biostatistics, Johnson & Johnson Vision, United States

Amy  Xia, PhD

Amy Xia, PhD

Vice President, Center for Design and Analysis, Amgen Inc., United States

As a deliverable under the Prescription Drug User Fee Amendments of 2017, the FDA launched the Complex Innovative Trial Design (CID) Pilot Meeting Program on August 29, 2018. The purpose of the program is to facilitate the advancement and use of complex adaptive, Bayesian, or other innovative clinical trial designs requiring simulations to determine operating characteristics. This session will give an update on the CID Pilot Meeting Program including a case study and provide a perspective on best practices for simulations in support of CID. Additionally, a group of speakers and panelists will discuss opportunities and challenges relative to the continued implementation of the program.

Learning Objective : At the conclusion of this session, participants should be able to:
  • Explain the concept of CID and the role of simulations in CID
  • Present a case study
  • Describe challenges and opportunities in applying CID

Speaker(s)

Dionne  Price, PhD

Dionne Price, PhD

Deputy Director, Office of Biostatistics, OTS, CDER, FDA, United States

Speaker

Telba  Irony, PhD, MS, MSc

Telba Irony, PhD, MS, MSc

Senior Scientific Director, Quantitative Sciences, Janssen R&D, United States

Speaker

Vladimir  Dragalin, PhD

Vladimir Dragalin, PhD

Vice President, Scientific Fellow, Janssen R&D, at Johnson & Johnson, United States

Industry Perspective on the Simulation Practices for Complex Innovative Designs

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