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Bethesda North Marriott Hotel and Conference Center

Oct 25, 2017 7:00 AM - Oct 27, 2017 3:00 PM

5701 Marinelli Road, , North Bethesda, MD 20852 , USA

DIA/FDA Oligonucleotide-Based Therapeutics Conference

Convening industry and health authorities to inform, educate, and share advancements in oligonucleotide-based therapeutic product development.

Poster Session and Networking Reception

Speaker(s)

Nancy  Griffith, PHD

Nancy Griffith, PHD

, Wave Life Sciences, United States

The Effects of Chiral Control on the Pharmacologic Properties of Antisense Oligonucleotides

Joe  Harford, PHD

Joe Harford, PHD

President & CEO, SynerGene Therapeutics, Inc., United States

A Targeted Nanocomplex that Actively Ferries Therapeutic Nucleic Acids Across the Blood-Brain Barrier

Zhong  Zhong

Zhong Zhong

Vice President, Biology, Wave Life Sciences, United States

DMD Exon 51 Skipping Efficiency and Dystrophin Protein Restoration Induced by WVE-210201: An Investigational Stereopure ASO

Petra  Kos, PHD, MPHARM

Petra Kos, PHD, MPHARM

Postdoctoral Fellow, UT Southwestern Medical Center, United States

miRNA-Loaded Lipid Nanoparticles for Ovarian Cancer Treatment

Meena  Meena, PHD

Meena Meena, PHD

Senior Director, Wave Life Sciences, United States

Preclinical Studies of WVE-120101 and WVE-12010: Investigational Stereopure ASOs for Huntington’s Disease (HD)

Hong  Jiang, MS

Hong Jiang, MS

Scientist I, Leal Therapeutics, United States

Impurity and Failure sequence Profile Change Due to Omission of the Capping Step in Synthesis of PS/PO Mixed Backbone ASOs

Silke  Klick, PHD

Silke Klick, PHD

Regulatory Director CMC, AstraZeneca, Sweden

Quality Aspects of mRNA Drug Products: How Do We Control Identity, Purity, and Potency?

Ruiting  Liang, PHD

Ruiting Liang, PHD

Senior Scientist, Alkermes, United States

A Control Strategy for GMP Manufacturing of Antisense Oligonucleotides Based on a Liquid DS Platform

Jennifer  Freedman, PHD

Jennifer Freedman, PHD

Assistant Professor, Duke Cancer Institute, United States

Development of a Novel Therapeutic Splice-Switching Oligonucleotide Targeting Race-Related Aggressive Prostate Cancer

Corrie L Gallant-Behm, PHD

Corrie L Gallant-Behm, PHD

Research Scientist III, Miragen Therapeutics, Inc., United States

Translatability of miR-29 PD Biomarkers from Preclinical Models to Mechanistic Proof of Concept in an MRG-201 Clinical Trial

Marcin  Kortylewski, PHD, MS

Marcin Kortylewski, PHD, MS

Professor, City Of Hope, Beckman Research Institute, United States

Dual Function Oligonucleotide CpG-STAT3 Inhibitor for B-Cell Lymphoma Immunotherapy

Mai Bailey Thayer, MS

Mai Bailey Thayer, MS

Senior Associate Scientist, Amgen Inc., United States

Ultra-Sensitive Locked Nucleic Acid Hybridization-Ligation ECL ELISA for Quantitative Measurement of siRNA

Girish R Chopda, PHD

Girish R Chopda, PHD

Associate Director, Nonclinical Development, Dicerna Pharmaceuticals, United States

Comparison of Subcutaneous and Intravenous Routes of Administration for Liver-Targeted RNAi Agents: Effect of PK-Modulating

Josh  Whisenand

Josh Whisenand

, TriLink BioTechnologies, United States

Innate Immune Focused Approaches to Maximize Messenger RNA Therapeutic Activity

Brent Allen Dickinson

Brent Allen Dickinson

Manager, Pharmacokinetics, Miragen Therapeutics, United States

Pharmacokinetic and Safety Data in Monkey and Human After IV Bolus Administration of MRG-106: An Inhibitor of miR-155

Anita G Seto, PHD

Anita G Seto, PHD

Associate Director, Translational Sciences, miRagen Therapeutics, United States

Phase 1 Trial Evaluating MRG-106: A Synthetic Inhibitor of microRNA-155 in CTCL Patients

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