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San Diego Convention Center

Jun 15, 2014 8:30 AM - Jun 19, 2014 12:45 PM

111 W Harbor Drive, , San Diego, CA 92101 , USA

DIA 2014 50th Annual Meeting "Celebrate the Past - Invent the Future"

Key Subgroup Analysis Issues in Clinical Trials

Session Chair(s)

Joachim  Vollmar, MSC

Joachim Vollmar, MSC

Executive Consultant, International Clinical Development Consultants LLC (ICDC), United States

This session will discuss key subgroup analysis issues arising in late-phase clinical trials, including statistical methods commonly used in exploratory and confirmatory subgroup analysis and applicable regulatory requirements.

Learning Objective : Identify commonly used exploratory and confirmatory subgroup analysis methods; Define statistical methods used for addressing multiplicity in clinical trials with pre-specified subgroups; Identify the factors that influence the selection of data mining methods used in exploratory subgroup analysis; Discuss key regulatory requirements in subgroup analysis.

Speaker(s)

David  Ohlssen, PHD

David Ohlssen, PHD

Senior Expert Methodologist, Novartis Pharmaceuticals Corporation, United States

The New CHMP Guideline on Subgroup Analysis: What's New?

Lilly  Yue, PHD

Lilly Yue, PHD

Deputy Director, Division of Biostatistics, CDRH/FDA, U.S. FDA, United States

FDA Perspective

Ilya  Lipkovich, PHD

Ilya Lipkovich, PHD

Senior Director, Center for Statistics in Drug Development, Innovation, IQVIA, United States

Key Statistical Considerations in Subgroup Analysis

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