Future of Evidence Workshop

There are many challenges in determining the long-term relative effectiveness of treatments, despite regulatory approval and robust clinical efficacy. The dilemma for payers is making an accurate assessment when evidence is derived from clinical studies that are extrapolated from outcomes of less than two years. This presentation will give several examples of the work that Vital Transformation has done for several clients harnessing Real-World Data. The most recent example includes evidence extracted from an academic medical center EHR dataset to measure the relapse-free survival (RFS) and cost of treating acute lymphocytic leukemia (ALL) with CAR-T compared to allogeneic hematopoietic cell transplant (HCT). It assesses the clinical effectiveness of CAR-T compared to the current standard of care.