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Emerging Issues in CRISPR and Gene Editing Symposium
Session Chair(s)
Philip (P.J.) Brooks, PhD
Deputy Director, Division of Rare Diseases Research Innovation
National Center for Advancing Translational Sciences (NCATS), NIH, United States
This session will discuss emerging issues related to gene editing, including standards for off-target effects, immunogenicity issues , and DNA base editors.
Learning Objective : Describe potential concerns related to immune responses in gene editing; Discuss the concept of on-target and off-target genome editing, and collaborative approaches to address this issue; Identify the difference between gene editing that involves making a double-stranded break in DNA versus DNA base editors that do not.
Speaker(s)
Immunogenicity Issues Related to Gene Editing
Zuben Erach Sauna, PhD, MS
FDA, United States
Principal Investigator, OTAT, CBER
Update on the Genome Editing Consortium
Samantha Maragh, PhD, MS
NIST, United States
Leader, Genome Editing Program
Base Editing: Performing Chemsitry on the Genome
Alexis C Komor, PhD
University of California San Diego, United States
Assistant Professor
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