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Novel Approaches for Accessing the CNS: Nonclinical and Clinical Challenges
Session Chair(s)
Richard Scheyer, MD
Vice President, Medical, Medpace, United States
This session will highlight new approaches in CNS-targeted therapeutics. These approaches to identify and develop therapies able to reach the CNS and address specific genetic perturbations are being pioneered in rare disease, and require disciplined approaches to study designs and execution.
Learning Objective : Design studies for advanced treatment modalities, with focus on CNS therapeutics. Identify and address hurdles in pre-clinical evaluation, identification of appropriate patients, and administration of treatments crossing or bypassing the blood brain barrier: Describe target engagement and biologic impact.
Speaker(s)
Dinah Duarte, MSC
Signal Management Lead, European Medicines Agency, Netherlands
William Elmquist, PHARMD, PHD
Director, Brain Barriers Research; Distinguished Prof, Dept. of Pharmaceutics, Univerity of Minnesota, United States
Richard Scheyer, MD
Vice President, Medical, Medpace, United States
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