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W-04: Treatment Comparisons of Timed Tests in Neurology





Poster Presenter

      David R. Bristol

      • President
      • Statistical Consulting Services, Inc.
        United States

Objectives

The time to completion of several tasks is censored when some patients do not complete all tasks, but references do not provide information for between-treatment comparisons in this case.

Method

Simulations are performed to compare various procedures for between-treatment comparisons of timed functional tests when some patients do not complete all tasks.

Results

Some standard timed functional tests are discussed. When some patients do not complete all tasks, the times to completion are censored and standard time to event analyses can be performed, ignoring the number of tasks completed. The number of tasks can be analyzed, ignoring the times to completion. A logical ordering of the possible outcomes is equivalent to analysis of the velocity=number of tasks/time.

Conclusion

The analysis of the velocity=number of tasks/time is proposed as an appropriate analysis of timed functional tests. Co-author: Nicole O. Stouffer