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Bethesda North Marriott Hotel and Conference Center

25 oct 2017 7:00 a.m. - 27 oct 2017 3:00 p.m.

5701 Marinelli Road, , North Bethesda, MD 20852 , USA

DIA/FDA Oligonucleotide-Based Therapeutics Conference

Convening industry and health authorities to inform, educate, and share advancements in oligonucleotide-based therapeutic product development.

Poster Session and Networking Reception

Speaker(s)

Nancy  Griffith, PHD

The Effects of Chiral Control on the Pharmacologic Properties of Antisense Oligonucleotides

, Wave Life Sciences, United States

Joe  Harford, PHD

A Targeted Nanocomplex that Actively Ferries Therapeutic Nucleic Acids Across the Blood-Brain Barrier

President & CEO, SynerGene Therapeutics, Inc., United States

Zhong  Zhong

DMD Exon 51 Skipping Efficiency and Dystrophin Protein Restoration Induced by WVE-210201: An Investigational Stereopure ASO

Vice President, Biology, Wave Life Sciences, United States

Petra  Kos, PHD, MPHARM

miRNA-Loaded Lipid Nanoparticles for Ovarian Cancer Treatment

Postdoctoral Fellow, UT Southwestern Medical Center, United States

Meena  Meena, PHD

Preclinical Studies of WVE-120101 and WVE-12010: Investigational Stereopure ASOs for Huntington’s Disease (HD)

Senior Director, Wave Life Sciences, United States

Hong  Jiang, MS

Impurity and Failure sequence Profile Change Due to Omission of the Capping Step in Synthesis of PS/PO Mixed Backbone ASOs

Scientist I, Leal Therapeutics, United States

Silke  Klick, PHD

Quality Aspects of mRNA Drug Products: How Do We Control Identity, Purity, and Potency?

Regulatory Director CMC, AstraZeneca, Sweden

Ruiting  Liang, PHD

A Control Strategy for GMP Manufacturing of Antisense Oligonucleotides Based on a Liquid DS Platform

Senior Scientist, Alkermes, United States

Jennifer  Freedman, PHD

Development of a Novel Therapeutic Splice-Switching Oligonucleotide Targeting Race-Related Aggressive Prostate Cancer

Assistant Professor, Duke Cancer Institute, United States

Corrie L Gallant-Behm, PHD

Translatability of miR-29 PD Biomarkers from Preclinical Models to Mechanistic Proof of Concept in an MRG-201 Clinical Trial

Research Scientist III, Miragen Therapeutics, Inc., United States

Marcin  Kortylewski, PHD, MS

Dual Function Oligonucleotide CpG-STAT3 Inhibitor for B-Cell Lymphoma Immunotherapy

Professor, City Of Hope, Beckman Research Institute, United States

Mai Bailey Thayer, MS

Ultra-Sensitive Locked Nucleic Acid Hybridization-Ligation ECL ELISA for Quantitative Measurement of siRNA

Senior Associate Scientist, Amgen Inc., United States

Girish R Chopda, PHD

Comparison of Subcutaneous and Intravenous Routes of Administration for Liver-Targeted RNAi Agents: Effect of PK-Modulating

Associate Director, Nonclinical Development, Dicerna Pharmaceuticals, United States

Josh  Whisenand

Innate Immune Focused Approaches to Maximize Messenger RNA Therapeutic Activity

, TriLink BioTechnologies, United States

Brent Allen Dickinson

Pharmacokinetic and Safety Data in Monkey and Human After IV Bolus Administration of MRG-106: An Inhibitor of miR-155

Manager, Pharmacokinetics, Miragen Therapeutics, United States

Anita G Seto, PHD

Phase 1 Trial Evaluating MRG-106: A Synthetic Inhibitor of microRNA-155 in CTCL Patients

Associate Director, Translational Sciences, miRagen Therapeutics, United States

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