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San Diego Convention Center

15 jun 2014 8:30 a.m. - 19 jun 2014 12:45 p.m.

111 W Harbor Drive, , San Diego, CA 92101 , USA

DIA 2014 50th Annual Meeting "Celebrate the Past - Invent the Future"

Session Chair(s)

Keith K. Burkhart, MD

Keith K. Burkhart, MD

Senior Advisor for Medical Toxicology, DARS, OCP, OTS

FDA, United States

Learning Objective : Discuss new technology that predicts off-target drug-protein binding; Describe applications for use throughout a drug’s life cycle; Demonstrate a biological plausibility analysis for serotonin syndrome.

Speaker(s)

Laszlo A. Urban, DRSC, MD, PHD

Use of In Silico Approach for Safety Assessment of Clinical Candidates: Mitigation and Management for Clinical Drug Positioning

Laszlo A. Urban, DRSC, MD, PHD

Novartis Institutes for BioMedical Research, Inc., United States

Global Head, Preclinical Safety Profiling

Michael J. Keiser, PHD

Predicting Secondary Pharmacology from Drug Off-Target Networks

Michael J. Keiser, PHD

Seachange Pharmaceuticals Inc, United States

Assistant Professor, UCSF; Founder

Keith K. Burkhart, MD

Use of In Silico Protein Binding Predictions in Postmarket Safety Signal Analysis and Biological Plausibility

Keith K. Burkhart, MD

FDA, United States

Senior Advisor for Medical Toxicology, DARS, OCP, OTS

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