Continuing Education credits are not available for the archived offering.

This archived webinar is available for purchase through November 5, 2015.
Duration: 1 hour 21 minutes

Series Overview

These core lectures will focus on the essentials of clinical pharmacology in drug development. They will outline basic pharmacological and therapeutic principles that show how drugs get into the body, how they produce their effects, what happens to them in the body, and how evidence of their therapeutic effect as well as unwanted effects are assessed. The information is vital to an understanding of how drugs are to be used safely and effectively. The principles will be illustrated by practical applications offered by examples from real experience.

Five lectures will cover the following topics:

• Pharmacokinetics
• Pharmacodynamics
• Principles of Modeling and Simulation
• Determining the Safe First Human Dose
• Assessment of QT Prolongation

Part 1: Fundamentals of Clinical Pharmacology: Pharmacokinetics

A basic understanding of pharmacokinetic and pharmacodynamic principles is necessary for employees in modern pharmaceutical development to understand strategies employed for appropriate labeling, formulation selection, safety and efficacy evaluation. In this webinar the basic principles of pharmacokinetics (what the body does to a drug) will be explained. 

This session will focus on the following topics:

• What is pharmacokinetics and pharmacodynamics?
• The basic principles of drug absorption, distribution, metabolism, and elimination will be explained
• The importance of factors influencing effective and safe use of a medicine will be discussed