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Clinical Statistics for Nonstatisticians


Session 10: A Trial for Equivalence

Session Chair(s)

Rafe  Donahue, PhD

Rafe Donahue, PhD

  • Senior Director, Biometrics
  • Sierra Oncology, United States
Discuss statistical issues in trials designed to demonstrate clinical equivalence or non-inferiority. Special attention will be directed toward proper ways to derive inferences in such trials.
  • Sample size determination
  • Hypothesis testing approach
  • Confidence interval approach
  • Interpreting the results

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