Real-World Evidence Conference

RWD/RWE is increasingly used to support HTA, reimbursement, and market access decisions, but its impact depends on whether the evidence is credible, relevant to local decision questions, and actionable across the access lifecycle. This session will examine practical strategies for translating RWD into decision-ready RWE, including fit-for-purpose data selection, transparent causal and statistical methods, use in comparative effectiveness and economic evaluation under uncertainty, and alignment with payer and HTA evidence needs. Through examples from HTA submissions and market access contexts, speakers will discuss where RWE can reduce uncertainty, where it may be discounted, and how sponsors can plan lifecycle evidence to improve decision usefulness. Attendees will leave with a cross-functional framework for designing RWE that connects methodology, HTA decision-making, and access strategy.