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Bethesda North Marriott Hotel and Conference Center

Feb 02, 2026 10:00 AM - Feb 04, 2026 12:45 PM

5701 Marinelli Road, North Bethesda, MD 20852

Regulatory Submissions, Information, and Document Management Forum

Don't miss the latest trends, innovations, and best practices in regulatory submissions, information, and document management (RSIDM)!

Session 2: FDA Electronic Submissions Update

Session Chair(s)

Jonathan  Resnick, PMP

Jonathan Resnick, PMP

Advisor, Office of Digital Transformation, FDA, United States

Seyoum  Senay, MS

Seyoum Senay, MS

Supervisory Operations Research Analyst, CDER/OBI, FDA, United States

This session will provide information related to electronic submissions. Topic areas will address eCTD, ESG, GSRS, CDER Nextgen Portal, and a proof of concept around modernizing the Information Request process. Experts from these areas will discuss recent updates and be available during the FDA Ask the Regulator session to answer questions.

Update on eCTD v3.2.2 & v4.0 Submissions
Jessica Bernhardt, FDA

Updates to eCTD for v3.2.2 and v4.0
Heather Crandall, FDA

FDA CDER NextGen Portal
Seyoum Senay, FDA

FDA’S Global Substance Registration System (GSRS) and Submitting Structure Data (SD) File to have Unique Ingredient Identifiers (UNIIs) for FDA-regulated Products
Siba Bhattacharyya, FDA

FDA CDER Information Request (IR) Modernization: PDUFA VII IR Demonstration Project
Jonathan Resnick, FDA

Learning Objective :
  • Discuss updates to FDA’s eCTD program including eCTD v4.0, webpage edits, updates to specification and guidance, common validation issues
  • Identify updates to CDER’s NextGen Portal and when to use it
  • Explain benefits of FDA’s Global Substance Registration System
  • Share updates to FDA’s ESG program including transition to ESG NextGen, webpage edits, overall benefits
  • Explain how the IR Modernization proof of concept can address pain points

Speaker(s)

Jessica  Bernhardt, MS

Update on eCTD v3.2.2 & v4.0 Submissions

Jessica Bernhardt, MS

IT Project Manager ODT, FDA, United States

Heather  Crandall, MA

Updates to eCTD for v3.2.2 and v4.0

Heather Crandall, MA

Business Informatics Specialist, OBI, FDA, FDA, United States

Siba P Bhattacharyya, PhD

Global Substance Registration System (GSRS) and Submitting Structure Data File (SDF) to FDA

Siba P Bhattacharyya, PhD

Health Scientist, OC/ODT/ODAR/HIS, FDA, United States

Jonathan  Resnick, PMP

FDA’S Global Substance Registration System (GSRS) and Submitting Structure Data (SD) File to have Unique Ingredient Identifiers (UNIIs) for FDA-regulated Products

Jonathan Resnick, PMP

Advisor, Office of Digital Transformation, FDA, United States

Seyoum  Senay, MS

FDA CDER NextGen Portal

Seyoum Senay, MS

Supervisory Operations Research Analyst, CDER/OBI, FDA, United States

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